Product show
Bovidone K

【Detail】

Chemical Description
◆ Product name: Povidone K
◆ Brand name:  BOVIDONE® K 
◆ CAS NO.:9003-39-8
◆ INCI Name: Polyvinylpyrrolidone (abbr. PVP)
◆ CEP Reg. No: 2014-372 
   DMF Reg. No: 29049
◆ Chinese Excipient Registration No. of BOVIDONE® K30: F20170000142


Physical and Chemical properties
-- Freely soluble in water and a variety of organic solvents;
-- Free-flowing, Hygroscopic powder, solubilization, physiological compatibility, high adhesive ability;
 

Typical Properties


Specification

Product

K-Value

Mv.

Impurity A

ppm

Peroxides

ppm

2-P%)

Element Impurity

BOVIDONE® K15

12.8-17.3

4500-9700

≤10.0

≤400

≤3.0

Fulfil ICH Q3D

BOVIDONE® K17

15.3-18.4

7100-11000

≤10.0

≤400

≤3.0

Fulfil ICH Q3D

BOVIDONE® K25

22.5-27.0

19300 -31100

≤5.0

≤200

≤3.0

Fulfil ICH Q3D

BOVIDONE® K30

27.0-32.4

31700-51400

≤5.0

≤150

≤2.0

Fulfil ICH Q3D

BOVIDONE® K90

81.0-97.2

790000-1350000

≤10.0

≤400

≤3.0

Fulfil ICH Q3D

 

Applications
◆ The optimum binder for solid preparations, suitable for wet granulation, dry granulation, direct pressing and fluidized bed granulation, especially for quick-release and anhydrous preparations, as well as for drugs with poor water solubity, water sensitivity and poor compressibility. It can effectively improve the compressibility of particles, improve the adhesion and hardness of tablets, and promote the release of drugs.
◆ Used as coating agent of active pharmaceutical ingredients enhance drug stability;
◆ Used as suspension stabilizer, increase the suspension stability of oral liquid preparation.
◆ Used as solubilizer to increase the solubility and bioavailability of insoluble drug preparations.
 

Packing and Storage
◆ Packed in 25kg or 50kg fiber or plastic drum, inner lined with double medicinal polyethylene film bag.
◆ Stored in dry place at room temperature. 
 

Contact us

ADD: She Xian Circular economy zone, Huangshan City, Anhui Province, China

P.C.: 245200

Tel: +86 571 81671881

Fax: +86 571 87358796

Email: sales@bonsunpvp.com

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